EPOS2020/EUFOREA expert opinion on defining disease states and therapeutic goals in CRSwNP

• DOI: 10.4193/rhin23.415
• Publication Date: 2024-01-13T15:11:20Z
• Authors: W J Fokkens; E De Corso; V Backer; M Bernal-Sprekelsen; L Bjermer; C von Buchwald; A Chaker; Z Diamant; P Gevaert; J Han; C Hopkins; V Hox; L Klimek; V J Lund; S Lee; A Luong; J Mullol; A Peters; O Pfaar; S Reitsma; S Toppila-Salmi; G K Scadding; A R Sedaghat; A-S Viskens; M Wagenmann; P W Hellings
• Keywords: Chronic Rhinosinusitis; Expert opinion; Nasal Polyps; Disease management

Severe chronic rhinosinusitis with nasal polyps (CRSwNP), a form of diffuse bilateral (usually type 2) CRS, is debilitating disease significant impact on quality life (QoL). With novel knowledge and treatment options becoming available, there growing need to update or revise key definitions enable communication across different specialties dealing agree goals care in CRSwNP. The European Forum for Research Education Allergy Airway diseases (EUFOREA) EPOS expert members discussed how measure responses set new In this paper consensus list related CRSwNP provided: control, remission, cure, recurrence/exacerbation, treatable traits, remodeling, progression, modification. By providing these definitions, the involved experts hope improve between all stakeholders use routine care, basic clinical research international guidelines aimed harmonize optimize standard patients future.