Delivery Outcome in Women with Major Sickle Cell Syndrome: A Comparative Study of the Homozygous Forms “SS” versus the Heterozygous “SC”

• DOI: 10.4236/ojog.2015.512100
• Publication Date: 2015-10-27T22:51:41Z
• Authors: Amah Biova Adama-...; Abdoul-Samadou Ab...; Kossi Edem Logbo-...; Kodjo Fiagnon; Akila Bassowa; Koffi Akpadza
• Keywords: 03 medical and health sciences; 0302 clinical medicine; 3. Good health

Objectives: To determine the prevalence of women who delivered in two major sickle cell syndromes, “SS” and “SC”, to identify maternal early neonatal prognosis inherent each form. Material Methods: This is a comparative, descriptive retrospective cross-sectional study 226 files carrying syndrome (66 cases form versus 160 “SC” form), collected from May 2008 2013 at Gynecology Obstetrics Clinic Sylvanus Olympio’s University Hospital Lomé. Data were processed by Epi Info 6 software. For comparison variables, Chi-2 test Fisher with significance as p syndromes represent 0.8% all deliveries during period. Caesarean section, especially prophylactic one, was dominant mode delivery. The SS forms have been exposed more vaso-occlusive crises (22.7% vs. 13.1%; = 0.04, OR 0.31), blood transfusion (57.6% 29.4%; 7 × 10-5, 3.2) puerperal infections (p gave exposure greater morbidity. Resuscitative measures adults newborns should be reinforced delivery time these “at-risk-pregnancies”.