Eosinophil cationic protein mRNA expression in children with bronchial asthma

• DOI: 10.4238/2015.november.13.11
• Publication Date: 2015-11-16T10:45:52Z
• Authors: H.Y. Yu; X.Y. Li; Z.F. Cai; L. Li; X.Z. Shi; H.X. Song; X.J. Liu
• Keywords: Pathogenesis

Studies have shown that eosinophils are closely related to pathogenesis of bronchial asthma. Eosinophils release eosinophil cationic protein (ECP), which plays an important role in infection and allergic reactions. Serum ECP mRNA expression children with asthma has not been adequately investigated. We analyzed serum 63 21 healthy by using reverse-transcriptase polymerase chain reaction understand the The were segregated into acute-phase stable-phase groups, based on severity illness. (0.375 ± 0.04) was significantly higher than controls (0.20 0.02; P < 0.05). Additionally, group showed level (0.44 0.06) those (0.31 0.03) control groups 0.05), while markedly Detection possible applications diagnosis treatment