Systematic primary aspiration in acute myocardial percutaneous intervention: a multicentre randomised controlled trial of the export aspiration catheter

• DOI: 10.4244/eijv4i2a40
• Publication Date: 2011-02-03T14:41:38Z
• Authors: Bernard Chevalier; Martine Gilard; Irene Lang; Philippe Commeau; John Roosen; Michel Hanssen; Thierry Lefevre; Didier Carrié; Antonio Bartorelli; Gilles Montalescot; Keyur Parikh
• Keywords: Clinical endpoint; TIMI; Target lesion

It is unclear whether primary aspiration can prevent distal embolisation and thereby improve myocardial perfusion in patients presenting with acute infarction (AMI) within 12 hours after onset.At 24 centres Europe India, 249 AMI were randomised to the Export catheter (Medtronic Vascular, Santa Rosa, CA, U.S.A.) followed by stenting (N=120) or conventional without (N=129). There no significant differences between 2 groups baseline characteristics target lesion TIMI scores. Procedure time was 36.7 +/- 18.0 minutes for versus 34.5 21.5 (P=0.08). Debris obtained from 85.3% of arteries. The use a bailout technique significantly lower than (5.8% vs. 14.7%, P=0.02). For endpoint combined rate blush grade 3 and/or ST-segment resolution >50% assess perfusion, superior (85.0% 71.9%, P=0.025). Immediately postprocedure, 35.8% 25.4% (P=0.094). At 60 post procedure, 73.5% 64.8% (P=0.218). Primary also associated higher postprocedure corrected frame count (20 14.9 22.8 14, 30 days, there treatments major adverse cardiac cerebral events.Compared stenting, improved reperfusion flow 0 1. Further study involving larger numbers warranted its effect on longer-term clinical outcome.