Coinfection with Plasmodium falciparum and Schistosoma haematobium: Additional Evidence of the Protective Effect of Schistosomiasis on Malaria in Senegalese Children

• DOI: 10.4269/ajtmh.12-0431
• Publication Date: 2013-12-10T04:51:24Z
• Authors: Magali Lemaitre; Laurence Watier; Valérie Briand; André Garcia; Jean Yves Le Hesran; Michel Cot
• Keywords: Schistosoma

Parasitic infections are associated with high morbidity and mortality in developing countries. Several studies focused on the influence of helminth malaria but nature biological interaction is under debate. Our objective was to undertake a study explore measure excreted egg load caused by Schistosoma haematobium Plasmodium falciparum parasite densities. Ten measures density two schistosomiasis urinary excretion over 2-year follow-up period 178 Senegalese children were considered. A linear mixed-effect model developed take data dependence into account. This work showed that light S. infection (1–9 eggs/mL urine) presented lower P. densities than not infected ( P < 0.04). Possible changes coinfections should be considered anti-helminth treatment vaccination development.