A Case of Primary Amebic Meningoencephalitis

• DOI: 10.4269/ajtmh.1978.27.29
• Publication Date: 2017-05-10T17:09:48Z
• Authors: E. O. Hoffmann; C. Garcia; J. Lunseth; P. McGarry; J. Coover
• Keywords: Naegleria fowleri; Naegleria; Amoebiasis

A 56-year-old alcoholic developed primary meningoencephalitis and died 3 weeks later. Autopsy revealed multiple areas of necrosis acute granulomatous inflammation in the brain pancreas. Trophozoites cysts were discovered trophozoites alone Morphologic studies some parasitic features described as characteristic for Naegleria, but clinical, histological immunohistological favored an Acanthamoeba infection. This study calls caution use pure morphological criteria differential diagnosis Naegleria humans. Cultural characteristics, immunohistology serologic tests are probably more reliable differentiating these parasites.