Combined ultrasound and serologic screening for hepatic alveolar echinococcosis in central China.

• DOI: 10.4269/ajtmh.2002.66.23
• Publication Date: 2017-05-10T17:28:37Z
• Authors: Gitte Bartholomot; Dominique A Vuitton; Said Harraga; Da Zhong Shi; Patrick Giraudoux; Guy Barnish; Yun Hai Wang; Calum N L MacPherson; Philip S Craig
• Keywords: Echinococcus multilocularis; Echinococcus; Alveolar echinococcosis

Alveolar echinococcosis (AE), caused by Echinococcus multilocularis, is a zoonotic helminthic disease that can mimic malignancy. In the 1970s, foci of were found in central China. The aim present study was to estimate prevalence AE humans 2 districts south Gansu Province, China, use ultrasound and serology. After answering an epidemiological questionnaire, 2,482 volunteers from 28 villages underwent ultrasound. Serology via enzyme-linked immunosorbent assay for antibody activity performed on whole blood collected filter paper all subjects; serum subjects with abnormal image; randomly chosen either had no lesions or atypical lesions. At least one (25.3%) image observed 630 screened. A typical lesion progressive 84 (3.4%). Serologies positive 77 (96%) 80 patients who AE. Ultrasound useful screening endemic regions.