REDUCTION OF MALARIA DURING PREGNANCY BY PERMETHRIN-TREATED BED NETS IN AN AREA OF INTENSE PERENNIAL MALARIA TRANSMISSION IN WESTERN KENYA

• DOI: 10.4269/ajtmh.2003.68.50
• Publication Date: 2018-09-01T06:20:04Z
• Authors: FEIKO O. TER KUILE; DIANNE J. TERLOUW; PENELOPE A. PHILL...; WILLIAM A. HAWLEY; JENNIFER F. FRIEDMAN; SIMON K. KARIUKI; YA PING SHI; MARGARETTE S. KOL...; ALTAF A. LAL; JOHN M. VULULE; BERNARD L. NAHLEN
• Keywords: Mosquito net

The impact of insecticide (permethrin)-treated bed nets (ITNs) on malaria in pregnancy was studied a rural area western Kenya with intense perennial transmission. All households 40 79 villages were randomized to receive ITNs by January 1997. distributed control two years later. Complete data birth outcome available 2,754 (89.6%) 3,072 deliveries. Women (n = 780) followed monthly throughout 19 villages. Among gravidae 1-4, associated reductions 38% (95% confidence interval [CI] 17-54%) the incidence parasitemia and 47% CI 6-71%) severe malarial anemia (hemoglobin level < 8 g/dL parasitemia) during pregnancy. At time delivery, mean hemoglobin levels 0.6 0.01-1.2 g/dL) higher, prevalence placental or maternal reduced 35% 20-47%), low weight 28% 2-47%) 1-4 from ITN No beneficial observed five higher. In areas transmission, permethrin-treated reduce adverse effect first four pregnancies.