Impact of Detection Mode in a Large Cohort of Women Taking Part in a Breast Screening Program

• DOI: 10.4274/ejbh.galenos.2022.2021-11-8
• Publication Date: 2022-04-01T08:12:47Z
• Authors: Marilina García; Maximino Redondo; Irene Zarcos; Javier Louro; Francisco Rivas-Ruiz; Teresa Téllez; Diego Pérez; Francisco Medina ...; Kenza Machan; Laia Domingo; Maria del Mar Vernet; Maria Padilla-Ruiz; Xavier Castells; Maria Sala
• Keywords: Breast screening; Breast Cancer Screening

The aim of this study was to evaluate the existing survival rate and clinical-pathological differences among patients with breast cancer detected by mammographic screening.This multicenter cohort examined 1,248 who took part in a national screening program for early detection over an eight-year period.Of two patient subgroups (interval screening), we found significant distribution prognostic factors, interval cases presenting at lower mean age (p = 0.002), higher percentages human epidermal growth factor receptor 2 (HER-2) or triple negative luminal A B carcinomas 0.001), advanced stages (p<0.001), hormone expression poorer differentiation (p<0.001) (p<0.001). Among group, tumors during first round had significantly frequency comorbidities 0.038) tendency (p<0.1) be diagnosed as than incident cases.Our results highlight that are frequently characterized more benign phenotype rest subgroups, which could help when stratifying risk death selecting best treatment option each patient.