The Frequency of Sarcopenia and Associated Factors in Older Patients with Rheumatoid Arthritis

• DOI: 10.4274/ejgg.galenos.2020.314
• Publication Date: 2020-07-29T06:05:06Z
• Authors: İrfan Karahan; Sevgi Aras; Murat Varlı; Esat Çınar; Özlem Karaarslan ...; Teslime Atlı
• Keywords: 03 medical and health sciences; 0302 clinical medicine

sarcopenia in early 2018 and emphasized the importance of muscle quality (2).Etiopathogenesis includes age, endocrinological changes, nutritional status, comorbidities, defective immune response, chronic drug use, etc (3).On other hand, rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disorder that leads to deformities, disabilities, impairment physical acitivity extraarticular involvements.RA most frequent one between inflammatory arthritis.Also, muscle-specific symptoms signs are common Objective: Rheumatoid systemic, disease.On Geriatric syndrome characterized by decrease mass strength.Identifying detecting factors associated with critical for screening treatment older patients RA.Materials Methods: First off, Muscle Mass index Free Fat 30 young, healthy males females were assessed using bioimpedance analyzer find cut-off values diagnosis.Then, 100 RA over 65 years recruited same test, value 2 standard deviation below calculated levels diagnosed as having low mass.Patients who had plus (low handgrip strength or gait speed) sarcopenic.In addition, sample was divided into two groups sarcopenic non-sarcopenic.Demographic characteristics, medication history, value, daily life activities, frailty rate, malnutrition hemoglobin level, 25-OH vitamin D glomerular filtration factor, anti-cyclic citrullinated peptide seropositivity, erythrocyte sedimentation rates (ESR) C-reactive protein (CRP) level compared groups. Results:The group than group.Nobody found use any biological agent group, but 8 nonsarcopenic used agents previously.Malnutrition rate dependence activities living higher non-sarcopenic group.Not standing, both similar Disease Activity score-28; ESR CRP group. Conclusion:The prevalence rises aging, malnutrition, frailty.Accompanying an disease like RA, causes dependence, mortality at rates.Overall, its consequences should be considered geriatric population.