The Distribution of Different Types of Diabetes in Childhood: A Single Center Experience

• DOI: 10.4274/jcrpe.5204
• Publication Date: 2017-11-24T08:12:31Z
• Authors: Belma Haliloğlu; Saygın Abalı; Fuat Buğrul; Enes Çelik; Serpil Baş; Zeynep Atay; Tülay Güran; Serap Turan; Abdullah Bereket
• Keywords: Diabetic ketoacidosis; Single Center; Ketoacidosis

Type 1 diabetes (T1D) is the most common cause of in childhood but type 2 (T2D) and maturity onset young (MODY) are emerging as noteworthy causes at ages. The aim to determine distribution, trends clinical features different types one tertiary center.The records children adolescents aged 0-18 years who were diagnosed “diabetes/persistent hyperglycemia” between January 1999 December 2016, reviewed. Clinical laboratory characteristics patients diagnosis recorded.The mean ± standard deviation age 835 (48.7% females) was 8.8±4.4 years. Eighty-four percent T1D, 5.7% T2D, 5.3% MODY 5% being cases other diabetes. frequency diabetic ketoacidosis (DKA) severe DKA T1D 48.4% 11.6%, respectively. Fourteen (29.2%) with T2D presented ketosis two them (4.2%) had diagnosis. Antibody positivity 83.1% 14.8% T2D. A statistically significant increase has clearly been demonstrated recent a 1.9%, 2.4% 7.9% 1999-2004, 2005-2010 2011-2016, respectively (p<0.001). In MODY, genetic analysis performed 26 (59%) HNF1A GCK gene mutations detected 3 (11.5%) 14 (53.8%) patients, respectively.Although frequent DM childhood, trend towards notable our population.