Is There a Need for Such a Naming: Seronegative Primary Sjogren’s Syndrome?

• DOI: 10.4274/tji.galenos.2021.85047
• Publication Date: 2021-12-21T12:07:17Z
• Authors: Samet Karahan; Aycan Karabulut
• Keywords: Hypergammaglobulinemia; Rheumatism; Rheumatoid factor

Objective: Autoantibodies such as rheumatoid factor, anti-nuclear antibody, anti-Ro/SSA, and anti-La/SSB have an important role in the diagnosis of primary Sjogren's syndrome (PSS), but are not essential seronegative PSS when there is at least one focus minor salivary gland biopsy.The aim this study was to compare clinical serological differences between patients with seropositive PSS. Materials Methods:The included 273 who were followed up Kayseri City Training Research Hospital, a tertiary hospital, June 2018 July 2021.The based on 2016 American College Rheumatology/European League Against Rheumatism classification criteria.Autoantibodies detected 45 (16.5%) patients, they evaluated having PSS.Clinical laboratory parameter data all collected retrospectively from hospital database, compared PSS.Results: Females constituted 93.9% (n=214) group 91.1% (n=41) group.The mean age 47.87±9.07years 44.34±11.48years (p=0.026).No statistically significant determined groups terms sex distribution, features, rate leukopenia, lymphopenia, thrombocytopenia, hypergammaglobulinemia, hypocomplementemia, increased acute phase reactant.The median C4 value lower, IgG higher group.Conclusion: Clinical findings overlapped those PSS, made later