Meta-analysis of the frequency of intrauterine growth restriction and preterm premature rupture of the membranes in pregnant women with COVID-19

• DOI: 10.4274/tjod.galenos.2021.74829
• Publication Date: 2021-09-27T11:49:00Z
• Authors: Reza Bahrami; David A. Schwartz; Mojgan Karimi-Zarchi; Atiyeh Javaheri; Seyed Alireza Das...; Farzad Ferdosian; Mahmood Noorishadkam; Seyed Reza Mirjalili; Hossein Neamatzadeh
• Keywords: Intrauterine growth restriction; 2019-20 coronavirus outbreak

The impact of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in pregnancy has yet to be determined. Some studies indicate that SARSCoV- 2 infection may associated with a higher risk adverse outcomes pregnant women. Here, we performed meta-analysis estimate the frequency intrauterine growth restriction (IUGR) and preterm premature rupture membranes (PPROM) women Coronavirus disease-2019 (COVID-19). A comprehensive search was various databases, such as PubMed, Scopus, SciELO, MedRxiv, Web Science, find all relevant published before 10 February 2021. Cross-sectional consecutive case series reporting COVID-19 were included. total 24 studies, including 8 on IUGR 16 PPROM, selected. Pooled data showed frequencies PPROM 2.6% 9.9%, respectively. Analyses stratified by ethnicity Asian Caucasian COVID-19-infected 2.9% 2.0%, Moreover, 10.2% 5.8%, This However, well-designed, large-scale multicenter clinical are required improve validate these results.