Zingiber cassumunar, Guazuma ulmifolia, and Murraya paniculata Extracts as Antiobesity: In Vitro Inhibitory Effect on Pancreatic Lipase Activity

• DOI: 10.4308/hjb.18.1.6
• Publication Date: 2011-08-20T08:24:23Z
• Authors: DYAH ISWANTINI; RHOITO FROISTA SI...; ELIZABETH MARTATI...; LATIFAH KOSIM DAR...
• Keywords: Phytochemical

Zingiber cassumunar Roxb. (Bangle), Guazuma ulmifolia Lamk. (Jati belanda), and Murraya paniculata (Kemuning) have been used as slimming agents in jamu. A few researches performed studies on their potency antiobesity. The aim of this research was to investigate the Z. rhizome, G. ulmifolia, M. leaf extracts antiobesity agent based vitro inhibition activity pancreatic lipase activity. In research, water content determination, phytochemical assay, toxicity assay were toward single mixture cassumunar, resulted by water, ethanol, saponin extractions. results indicated that 100 ppm ethanol extraction had highest effect (29.17%), followed (25.66%), 60 leaves (25.13%) with ratio 25:25:25 (21.58%). These effects higher than inhibitory Xenical®/orlistat positive control, value 17.53%. Saponin crude lower other It suggested agent.