Preferential solvation of difenoconazole in binary solvent mixtures of methanol and ethanol in water at several temperatures

• DOI: 10.4314/bcse.v39i7.14
• Publication Date: 2025-04-24T12:56:17Z
• Authors: Adel Noubigh; Manef Abderrabba

The present investigation used the inverse Kirkwood-Buff integrals technique to determine best solvation parameters for DIF in two distinct alcoholic aqueous solutions, spanning a temperature range from 293.15 K 323.15 K. analysis demonstrated that values of displayed nonlinear trend concerning composition co-solvent. ( ) various solutions revealed variations were contingent upon concentration Notably, positive recorded mixtures with all compositions methanol and 0.00 < x1 0.33-0.35 0.50 1.00 ethanol. Conversely, demonstrates preference alcohol as solvent mixtures. At K, (1) + water (2) show highest preferential by alcohol, while ethanol exhibit lowest. KEY WORDS: Difenoconazole, Binary solvents, Inverse Kirkwood–Buff integrals, Preferential Bull. Chem. Soc. Ethiop. 2025, 39(7), 1425-1435. DOI: https://dx.doi.org/10.4314/bcse.v39i7.14