A Comparative Study on the Antimicrobial Susceptibility Patterns of Klebsiella and Enterobacter Species from the Lagos University Teaching Hospital

• DOI: 10.4314/jnica.v3i2.10720
• Publication Date: 2011-11-28T21:11:30Z
• Authors: I. E. Abe-Aibinu; V. Ohaegbulam; T. O. Odugbemi
• Keywords: Klebsiella; Amikacin; Klebsiella oxytoca

This paper sets to differentiate between Klebsiella and Enterobacter spp. Identification compare their antimicrobial susceptibility patterns at Lagos University Teaching hospital, a tertiary health institution. From March July 1998, total of 300 clinical specimens were processed in the Medical Microbiology Laboratory Hospital (LUTH). Isolates obtained from urine swabs wounds, ear, throat eye. was carried out by conventional methods investigated disk diffusion method. All isolates tested for beta-lactamase production. The samples yielded 185 species both (105 isolates) (80 isolates). highly susceptible amikacin, ceftazidime, ceftriaxone, aztreonam nalidixic acid (70%). However, ofloxacin norfloxacin observed be more effective on spp (90-93%) than Enterbacer (70-75%). Sixty-three percent 52.2% Gentamicin. gentamicin-resistant klebsiella while wound swabs. general, resistant (80%) cotrimoxazole, tetracycline amoxicillin-clavulanic acid. Ninety-four per cent 91% produced beta-lactamase. Multi-resistant strains these organisms appear endemic Hospital, though there no evidence any outbreak infections caused this study. result study will helpful empiric therapy In long run, continuous surveillance resistance should aid development sound antibiotic policy hospital. Key Words: spp, Comparative, Antibiotic Susceptibility. [J. Nig. Infection Control Assn. Vol.3(2) 2000: 14-17]