Impact of the type of ductus venosus agenesis and the presence of associated anomalies on prognosis

• DOI: 10.46328/aejog.v5i2.152
• Publication Date: 2023-09-19T01:52:02Z
• Authors: Züat Acar; Yusuf Başkıran
• Keywords: Ductus venosus; Agenesis; Foramen ovale (heart)

Objective: The Ductus Venosus (DV) connects the umbilical vein to inferior vena cava. With a portocaval pressure gradient, well-oxygenated blood in ductus venosus accelerates towards left sidewall of cava, directing preferentially cephalic and coronary circulation through foramen ovale (1). DV serves as shunt, expanding protect heart brain hypoxic conditions. Agenesis (DVA) is rare congenital abnormality with prevalence 0.03-0.07%. type DVA, along any additional anatomical or chromosomal anomalies fetuses significantly affects postnatal prognosis. Some DVA develop normally, while others may experience growth retardation, defects, other complications. In this study, we aimed evaluate frequency associated cases, examine impact each (intrahepatic extrahepatic venous drainage) on prognosis, contribute literature disease. Materials Methods: We conducted retrospective study all cases diagnosed prenatally at tertiary center between 2016-2019. Our reviewed obstetric data, anomalies, systemic genetic perinatal outcomes. Postnatal infants were followed up 6th month. Results: identified 16 agenesis. (intrahepatic-extrahepatic shunt), presence accompanying ultrasonographic findings, outcomes recorded. Generally, 7 out drained into portal system (44% - intrahepatic), 9 it system. Conclusion: potentially significant implications for affected infants. Early diagnosis, careful monitoring, appropriate management strategies are crucial optimize these patients. There's need future research better understand underlying etiology pathophysiology more effective treatment options individuals.