Levodopa-Induced Myocardial Infarction in a Patient with Parkinson'S Disease and Severe Coronary Artery Disease

• DOI: 10.4997/jrcpe.2019.108
• Publication Date: 2019-03-06T14:45:08Z
• Authors: Chen Fei Ng; Patrick WJ Tiau; Hui Jan Tan; MI Norlinah
• Keywords: Decarboxylase inhibitor; Vasomotor

Levodopa is the most effective medical treatment for Parkinson's disease (PD) to date. As dopamine known increase cardiac inotropism and vasomotor tone, peripheral decarboxylase inhibitor coadministered suppress conversion of levodopa dopamine. poses potential cardiovascular risks, thus its use in patients with existing coronary artery needs be carefully monitored. We report a case an elderly male newly diagnosed PD who developed non-ST-elevation myocardial infarction following (Madopar) initiation.