Multilayer intensity modulated contact interventional radiotherapy (brachytherapy): Stretching the therapeutic window in skin cancer

• DOI: 10.5114/jcb.2023.127837
• Publication Date: 2023-06-13T09:15:44Z
• Authors: Bruno Fionda; Elisa Placidi; Enrico Rosa; Valentina Lancell...; Gerardina Stimato; Martina De Angeli; Francesco Giusepp...; Patrizia Cornacch...; Frank-Andre Siebert; Luca Tagliaferri; Luca Indovina
• Keywords: Original Paper; skin cancer; brachytherapy; R; Medicine; interventional radiotherapy; therapeutic window; intensity modulated; 3. Good health

Interventional radiotherapy (IRT, brachytherapy) is a highly effective treatment method for non-melanoma skin cancer (NMSC). Traditionally, the maximum depth of NMSC lesions considered eligible contact IRT was 5 mm; however, following several national surveys and recent recommendations, such cut-off, thicker than mm may be treated by IRT. The use image guidance in defining actual treating to correctly identify clinical target volume (CTV) prevent unnecessary toxicity paramount importance. aim paper describe multilayer arrangement catheters treat mm, thus proposing an example dynamic intensity modulated IRT, using different catheter-to-skin distance sources reach best CTV coverage maximally reduce excess dose skin.