BREAST CANCER IN PAKISTAN - AN UPDATED OVERVIEW

• DOI: 10.51642/ppmj.v33i04.531
• Publication Date: 2023-05-17T05:46:55Z
• Authors: Ghazala Rubi; Maria Amir; Naeem Ashraf; Amir Bashir; Hina Andaleeb

Breast cancer is a leading cause of mortality in Pakistan due to cancer in females. Breast cancer has subtypes that inflict differently and owe to various factors that include our lifestyle and genetics. Pakistan has enhanced percentage in developing breast cancer in fourth decade of life in women. Numerous genomics and proteomics studies are being conducted in Pakistan for prognosis, diagnosis and treatment of breast cancer. This review focuses on the mutations in BRCA1/2 genes and other such genomic biomarkers. Moreover, this review emphasizes the advancements made in Pakistan for proteomic and metabolomics diagnosis of carcinoma.