Clinical–epidemiological profile of confirmed cases of osteoarticular tuberculosis

• DOI: 10.5194/jbji-8-11-2023
• Publication Date: 2023-01-05T10:58:38Z
• Authors: Caroline Thomaz P...; Priscila Rosalba ...; Vladimir Cordeiro...; Angélica Makio do...; Vanessa Ferreira ...; Ana Lucia Lei Mun...
• Keywords: Appendicular skeleton

Introduction: tuberculosis (TB) remains a major cause of morbidity and mortality worldwide. The incidence TB has increased since the 1980s. Given increasing prevalence worldwide, osteoarticular (OATB) is significant health problem. Methods: retrospective study case series hospitalized patients with confirmed OATB by culture or histopathological examination who were seen at reference orthopedic hospital in São Paulo, Brazil, from 2014 to 2019. Results: thirty bone joint main sites spine (83.3 %) appendicular skeleton (26.7 %). Indication surgical treatment was significantly related need for hospitalization ( p=0.009 ) length stay p=0.005 ). Presence sequelae end correlated presence motor deficit time diagnosis p=0.035 as well initial functional limitation p=0.025 high value C-reactive protein p=0.037 Conclusions: delay onset clinical laboratory signs cases infections hinders early disease, resulting complications sometimes requiring consequently leading prolonged stay, evidence inflammatory activities, neurological deficits.