Association of Reproductive Parameters with Dermatoglyphics in Breast Cancer Patients, Healthy and High-Risk Individuals

• DOI: 10.5195/ijms.2022.1750
• Publication Date: 2023-03-06T15:26:23Z
• Authors: Rahul Rangan; Swapna Shedge; Satish Kakade
• Keywords: Dermatoglyphics; Menarche; Genetic predisposition

Background Breast cancer has a wide array of risk factors, and its confounding reproductive aetiologies have been paramount in defining the predictive ability disease. Similarly, strong link between qualitative dermatoglyphic patterns predisposition to breast well documented through genetic linkage. Therefore, this study aimed discern affiliation aforementioned factors cancer. Methods The was carried out 3 groups 90 age-matched individuals - patients, high-risk healthy individuals. A detailed history taken including such as age at menarche, menstrual regularity, menopause (if attained), breastfeeding, obstetric parameters first live birth. Qualitative dermatoglyphics were procured standardised ink paper method get remarkable rolled fingerprint. variations gynaecological studied their significance computed using chi-square test on InStat software where p values < 0.05 considered significant with 95% confidence interval. Results Highly (p<0.0001) found all higher frequency whorls arches an equivalent predisposed Limitations Although might identified certain predominating frequency, consistency vary from place due differing according ethnicity. small number patients receiving chemotherapy experienced chemotherapy-induced adermatoglyphia loss fingerprints or very faint difficult perceive. These not included ensure maximum efficacy interpreting dermatoglyphics. Conclusion Previous attempts failed indices parameters, correlation variables three distinct groups. Most are diagnosed late majority presenting doctors advanced stages survival rates marginal, so by method, we can simple, practical, non-invasive easily affordable screening technique for above factors. This could also be employed non-symptomatic women who positive family part assessment early diagnosis treatment. paving way further research into prognostic abilities indices.