Etiology, Histopathology, Staging and Complication of Wilson Disease

• DOI: 10.52533/johs.2023.31209
• Publication Date: 2024-01-12T12:51:52Z
• Authors: Samar Alharbi; Saleh Bajahlan; Hassan Almohsin; Ahmed Altashani; Mohammed Alsairy; Abdulaziz Alsakhri; Mohamed Ali; Zeyad Alsehli; Abdullah Alilwit; Hassan AlMirza
• Keywords: Etiology; Liver disease

Wilsons disease is a disorder that occurs when there are mutations, in the ATP7B gene. This leads to problems with copper transport and metabolism body. In this review we explore causes, effects, symptoms management of disease. We delve into factors contribute condition how it affects livers’ ability handle copper. A key diagnostic feature presence "sunset glow" hepatocytes indicating buildup The manifests affecting organs such as liver nervous system, mind, blood, kidneys eyes. Due range an accurate diagnosis requires approach. Prognosis tailored treatment strategies can be aided by staging using Leipzig scoring system. discuss complications associated Highlight its impact on underscoring why timely crucial. section outlines approaches including medication remove from body or regulate zinc levels well dietary modifications control absorption. Regular monitoring through function tests, measurements neurological assessments essential for managing condition. Genetic counseling plays role helping individuals make decisions about their health comes cases where other treatments have failed inadequate, controlling preventing organ damage transplantation may considered resort option. Finally, conclude highlighting ongoing research continues improve our understanding refine methods strategies.