determination of phenolic compounds in prunus domestica fruits extract and its pharmacological activity

• DOI: 10.5272/jimab.2019251.2589
• Publication Date: 2019-06-27
• Authors: Shahm B. Mohammed; Taras V. Upyr; Olga M. Shapoval; Larysa V. Lenchyk; Kaloyan Georgiev
• Keywords: 0106 biological sciences; Medicine (General); diuretic; membrane-stabilizing effect; RK1-715; fruits; phenolic compounds; 01 natural sciences; hypouricosemic; R5-920; Dentistry; plum; extract

Qualitative composition and content of phenolic compounds in the liquid extract obtained from plum fruits have been studied. Five phenolic substances were found, as gallic acid, three hydroxycinnamic acids and rutin. The dominant substance was neochlorogenic acid (2320±42 mg/kg). Phenolic substances were identified in the extract and their amount determined by HPLC. Diuretic activity as diurnal spontaneous diuresis and forced diuresis, hypouricosemic and the membrane-stabilizing effects of plum liquid extract and its influence on the rheological properties of blood were studied.