dendritic action potentials and computation in human layer 2 3 cortical neurons
Adult
Male
Adolescent
Pyramidal Cells
Action Potentials
Neocortex
Dendrites
Middle Aged
3. Good health
Young Adult
Humans
Calcium
Female
Aged
DOI:
10.5281/zenodo.3758324
Publication Date:
2020-01-03
AUTHORS (10)
ABSTRACT
Human dendrites are special A special developmental program in the human brain drives the disproportionate thickening of cortical layer 2/3. This suggests that the expansion of layer 2/3, along with its numerous neurons and their large dendrites, may contribute to what makes us human. Gidon et al. thus investigated the dendritic physiology of layer 2/3 pyramidal neurons in slices taken from surgically resected brain tissue in epilepsy patients. Dual somatodendritic recordings revealed previously unknown classes of action potentials in the dendrites of these neurons, which make their activity far more complex than has been previously thought. These action potentials allow single neurons to solve two long-standing computational problems in neuroscience that were considered to require multilayer neural networks. Science , this issue p. 83
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