Comparative Study between Crystalloid Preloading and Coloading for Prevention of Hypotension in Elective Cesarean Section Under Spinal Anesthesia in a Secondary Care Hospital

• DOI: 10.5281/zenodo.3982580
• Publication Date: 2020-07-31
• Authors: Bhardwaj, Neha; Abhishake Thakur; Abhishek Sharma
• Keywords: 03 medical and health sciences; 0302 clinical medicine; coloading, preloading, hypotension, mephentermine, spinal anesthesia, cesarean; 3. Good health

The anesthesia of choice for majority of elective cesarean deliveries is spinal anesthesia, as it is easier to administer, quicker in action, lesser cost, less risk of anesthetic toxicity, minimum transfer of drug to the fetus and provides early ambulation. Maternal hypotension is the major complication associated with subarachnoid block, which can affect both mother as well as fetus. Earlier studies had shown good results of crystalloid preloading for the prevention of maternal hypotension after spinal anaesthesia.Now a days coloading is preferred over preloading as it increases intravascular volume during vasodilatory phase of sympathetic blockade and thus, causes less fluid redistribution and excretion. Hence, we undertook this study to compare the effect of preloading and coloading on prevention of hypotension after spinal anesthesia. Total number of participants in our study was 50.P (preloading) group as well as C (coloading) group consisted of 25 patients each. The systolic blood pressure dropped in both groups after spinal anesthesia but drop was more in P group (p< 0.001). Mephentermine requirement was also more in P group as compared to C group. Coloading of crystalloid fluid is a better method than preloading of crystalloids for prevention of maternal hypotension after Subarachnoid block.