Risk Management in Tianeptine Abuse in Turkey: A National Experience

• DOI: 10.5455/bcp.20130426010958
• Publication Date: 2013-05-01T13:10:12Z
• Authors: Nedim Durmus; Gamze Ozbilen; Yelda Kasap; Oguzhan Koyuncu; Osman Yildirim; Guven Artiran; Saim Kerman; Demet Aydinkaraha...
• Keywords: Tianeptine

Objective: Tianeptine is used in the treatment of major depressive episodes and has structural similarities with tricyclic antidepressants although it different pharmacological properties abuse potential among patients a history dependence or any drug alcohol. In this study, we aimed to evaluate safety problems risk management measures for tianeptine Turkey relation its potential.Methods: Adverse event reports noting use agent have been evaluated through retrospective examination databases Turkish Medicines Medical Devices Agency, Intercontinental Statistics (IMS), Uppsala Monitoring Centre (Vigiflow) Pharmaceuticals Track Trace System.Results: After three individual fatal cases were reported 2011 2012 associated increased received by department, included controlled substances list since October 2012.Conclusion: Although several advantages compared antidepressants, should be carefully observed especially