Genome-wide identification and characterization of interleukin-18 gene family in rainbow trout (Oncorhynchus mykiss)

• DOI: 10.5455/jabet.2024.d23
• Publication Date: 2024-02-18T19:25:22Z
• Authors: Sayed Bari; Md Hossen; Md Islam; Md Helal
• Keywords: Synteny; Pseudogene

Rainbow trout (Oncorhynchus mykiss) are cold freshwater fish species belonging to the Salmonidae family, and they hold significant economic importance in global aquaculture industry. The Interleukin-18 gene family plays a crucial role immune response of when combating viral infections. A wide range computational approaches were conducted investigate functions, phylogeny, expressions IL-18 genes. study found that there nine genes present on eight chromosomes trout, their encoded proteins predicted be distributed cytoplasm nucleus. Genetic structures, motif conserved domains analysis revealed same group have similar exons, motifs, domains. phylogenetic demonstrates divergence 38 from three into distinct subgroups across time. synteny evolutionary mechanisms, such as duplications mutations. In addition, research investigated expression liver tissues following infection with infectious hematopoietic necrosis virus (IHNV). These findings provide comprehensive understanding O. mykiss pathogenic infection.