Association of SII and AISI in patients with sepsis: A retrospective study

• DOI: 10.5455/medscience.2024.10.117
• Publication Date: 2025-03-01T18:36:41Z
• Authors: Ahmet Gurpinar; Huseyin Erdal; Hacer Kalayci
• Keywords: Association (psychology)

Sepsis, a life-threatening dysregulated immune response to infection, necessitates reliable biomarkers for early risk stratification and prognosis. Sepsis occurs when bacteria that cause an infection the body's overwhelming inflammatory reaction leads extensive tissue injury, organ dysfunction, can be deadly if not promptly addressed. This study investigates role of Systemic immune-inflammation index (SII), (SIRI) Aggregate Index Inflammation (AISI) score in patients with sepsis. retrospective included 127 diagnosed sepsis between November 2023 March 2024. Neutrophil, lymphocyte platelet levels statistically significant differences were observed groups (p<0.0001). However, indices calculated did show terms SII, SIRI, AISI (p<0.05). highlights SII as accessible, cost-effective assessing systemic inflammation predicting adverse outcomes research also emphasizes predictive significance AISI, which are straightforward regularly measured biomarkers. Further prospective studies warranted validate these findings explore their utility dynamic monitoring progression.