Evaluation of Antibacterial Activity of Fruit Juices on Clinical and non-Clinical Enterotoxigenic, biofilm-producing Methicillin Resistance Staphylococcus aureus

• DOI: 10.54692/lgujls.2024.0801322
• Publication Date: 2024-04-05T04:42:36Z
• Authors: Saba Riaz; Hafiza Iqra Abdu...; Asad Ali; Muhammad Hassan ...; Noor Aqsa; Sikander Sultan
• Keywords: Enterotoxigenic Escherichia coli

The drug-resistance behavior of Methicillin-resistant Staphylococcus aureus (MRSA) has made it difficult to treat. This study aimed discover some fruit juice's anti-MRSA potential and the presence enterotoxin genesin MRSA.MRSA strains were confirmed phenotypically by disc diffusion method. well-diffusion method Minimum inhibitory concentration (MIC)were used determine antibacterial effects juices. Congo red test ring tests performed analyze biofilm-forming ability. PCR detected staphylococcal genes Sea Seg. A total 90strains, which 26 nonclinical 64 clinical samples processed. Ciprofloxacin (CIP) was highly resistant MRSA in both groups. In isolates, Citrus reticulate shown maximum activity against 67.1% MRSA, whereas, Punicagranatum most effective for 46.1% isolated from non-clinical sources. inhibiting growth at >64μl/ml Both determined ability 57.60% 65.30% strains, respectively. Enterotoxin-producing gene 8% group only 2% group. Seg co-existence found same ratio showed that juices, especially pomelo, orange, pomegranate, have high activity. Enterotoxin play a role spread infections caused MRSA.