Relation between Cardio-Ankle Vascular Index and Coronary Artery Calcification or Stenosis in Asymptomatic Subjects

• DOI: 10.5551/jat.15149
• Publication Date: 2013-03-24T22:37:38Z
• Authors: Jun-Bean Park; Hyo Eun Park; Su-Yeon Choi; Min Kyung Kim; Byung-Hee Oh
• Keywords: Dyslipidemia

The cardio-ankle vascular index (CAVI) is an of arterial stiffness. We investigated the association CAVI with severity coronary artery calcification (CAC) and stenosis by computed tomography angiography (CTA) in asymptomatic population.A total 549 Korean individuals who underwent CTA were analyzed retrospectively. CAC measured assessed for correlation CAVI.The degree demonstrated a significant (r= 0.187, p<0.001 r= 0.212, score stenosis, respectively). After adjustment potential confounders, including age, gender, hypertension, diabetes mellitus, dyslipidemia, predefined cutoff value ≥8 was associated advanced (CAC ≥300) (stenosis ≥50%). Specifically, adjusted odds ratio (95% confidence interval) ≥300 ≥50% 3.57 (1.92-6.66) 2.81 (1.13-7.00), respectively. Additional inclusion improved predictive power receiver operating characteristic curves predicting atherosclerosis based on traditional risk factors; area under curve increased from 0.739 to 0.791 (p difference= 0.023), 0.761 0.842 (p= 0.032), respectively.CAVI reflects may be used as screening tool assessing subclinical atherosclerotic burden population.