The Uniqueness of Albumin as a Carrier in Nano Drug Delivery
01 natural sciences
0104 chemical sciences
DOI:
10.55544/jrasb.3.1.2
Publication Date:
2024-02-02T13:55:05Z
AUTHORS (6)
ABSTRACT
The quest for precision medicine hinges on targeted drug delivery, minimizing off-target effects while maximizing therapeutic impact. Among nanocarriers, albumin – the most abundant protein in human blood emerges as a uniquely biocompatible stealth bomber. Its inherent advantages, including exceptional biodegradability, prolonged circulation, and natural affinity diseased tissues, perfectly align with goals of personalized medicine. Albumin readily solubilizes poorly soluble drugs, enhancing bioavailability broadening arsenal. versatile surface allows modifications, enabling dual diagnosis treatment (theranostics) tailored to individual needs. While challenges remain optimizing loading targeting specificity, albumin-based nanocarriers hold immense promise revolutionizing healthcare, delivering potent therapeutics pinpoint accuracy. burgeoning field nanodrug delivery seeks redefine landscapes by engineering nanoscale carriers that meticulously deliver drugs their designated targets, systemic exposure efficacy. This pursuit aligns medicine, where treatments demand exquisite control over delivery. Within this intricate choreography, albumin, resident plasma, maestro, orchestrating symphony advantages make it prime candidate nanocarrier construction.
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