Sağlık Çalışanları SARS-CoV-2 Hasta Kohordunda Antikor Sürdürülebilirliği

• DOI: 10.5578/mb.20229807
• Publication Date: 2022-04-26T09:48:30Z
• Authors: Erhan Eser; Şebnem Şenol Akar; Sinem Akçalı; Talat Ecemiş; Pınar Erbay Dündar; Kübra Çiçek; Damla Akman; Ecem Tüzün; Gülsüm Şanlı Erke...; Zeynep Ceyda Buran; Zeynep Öykü Öztür...; Ferya Karadağ Yalçın
• Keywords: 0303 health sciences; 03 medical and health sciences

In this study, it was aimed to evaluate one-year follow-up of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) specific antibodies formed against the virus binding site, in a coronavirus disease-2019 (COVID-19) positive case cohort (n= 413) between period March 2020 December Manisa Celal Bayar University Hospital, until July 2021. SARS-CoV-2 were determined by chemiluminescent enzyme immunoassay (CLIA) method. Values 1.0 and above considered positive. Chi-square tests Joinpoint regression analysis (version 4.7.0) used statistical analyses. The mean age participants 34.9 ± 9.3 60.2% them women. Between 21-30 days after diagnosis COVID-19, total antibody level threshold value 72.2% 126) participants, while rate increased 79.1% 240) 31-60 day interval. following period, decreased 38.8% 108) 211st 240th. Antibody response could not be detected 76 (20.7%) 367 employees who have initially been followed up. percentage positivity prevalence ranged from 98.9% 96.1% 31-210th diagnosis, 291 whose diagnosis. According results analysis, curve showing broken at two points: first breaking point observed 181-210th (6-7 months) (p= 0.069), second 271-300th (9-10 (p< 0.001). As result, highest rates 30th disease onset maintained seven months diagnosis; 25% end year.