Clinical course of community-acquired respiratory syncytial virus pneumonia in newborns hospitalized in neonatal intensive care unit

• DOI: 10.5578/tt.4598
• Publication Date: 2013-12-11T12:51:12Z
• Authors: Banu AYDIN; Ayşegül ZENCİROĞLU; Dilek DİLLİ; Nurullah OKUMUŞ; M. Şah İPEK; Mustafa AYDIN; Nuran UZUNALIÇ; Nilay HAKAN; Ahmet Afşin KUNDAK; Arzu DURSUN; Nilgün KARADAĞ; Gülay KORUKLUOĞLU
• Keywords: Enteral administration

Respiratory syncytial virus (RSV) is a major cause of pneumonia in infants worldwide. We aimed to evaluate the clinical course community-acquired RSV newborns hospitalized neonatal intensive care unit.All diagnosed as were prospectively evaluated for infection between November 2010 and April 2011. Fifty-four specimens nasopharyngeal secretions tested parallel with RAT multiplex real time polymerase chain reaction (RT- PCR). Downes' score was used assess disease severity patients pneumonia.RAT has sensitivity 90% specificity 78.5%, PCR technique target assay. Four had secundum atrial septal defect (ASD) all four needed mechanical ventilation support. The first day positively correlated intravenous fluid requirement (p= 0.001, r= 0.48), total oxygen need 0.000, 0.63), re-enteral feeding 0.46). Blood pH 0.031, 0.46) negatively score. second higher ASD than those without (3.8 ± 2.6 vs. 2 1.1, p= 0.01). most possible risk factor longer hospital stay 0.02 OR: 1.9, CI 95% (1.1-3.2). All discharged from good health.RAT sensitive specific detecting infections newborns. Physicians may use evaluation pneumonia. In these patients, increased severity.