Klasyczna postać naciekającego zrazikowego raka piersi w materiale Krakowskiego Oddziału Centrum Onkologii: obraz kliniczny, wyniki leczenia, czynniki prognostyczne u chorych leczonych w okresie 1980–2005

• DOI: 10.5603/njo.2016.0003
• Publication Date: 2016-07-05T09:40:14Z
• Authors: Piotr Skotnicki; Łukasz Wohadlo; Beata Sas-Korczyńska; Marian Reinfuss; Jerzy W. Mituś; Tomasz Walasek
• Keywords: Progesterone receptor; Axillary lymph nodes

Introduction . Infiltrating lobular breast cancer (ILC) accounts for approximately 5–10% of all types. The purpose this study is to present the clinico-pathological characteristics and treatment results in patients treated classical variant ILC (C-ILC). Material methods analysis was performed group 220 with C-ILC between 1980 2005. Stage I or II found 67.7% patients, 172 (78.2%) tumour diameter lower than 5 cm (78.2%), 121 (55%) did not develop lymph node metastases. Immunohistochemical showed estrogen receptor positivity (80.9%), progesterone (72.7%) expression HER2/neu (3.7%). multifocal changes were 14 cases (6.4%). All received surgical treatment: mastectomy (189 — 85.9%) breast-conserving therapy (31 14.1%). adiuvant consisted radiotherapy (141 64.1%), chemotherapy (35 15.9%) hormonotherapy (120 54.5%). Results 10-year disease-free survival rate 65%. Multivariate that an independent statistically significant prognostic factor microscopic status axillary nodes. During follow-up development second observed 19 ( 8.6%) 55 (25%) developed distant Conclusions has some specific it possible perform breast- -conserving these cases. negative presence