Examination of the Use Survey and the Usefulness of Tramadol in Cancer Pain Patients

• DOI: 10.5649/jjphcs.42.69
• Publication Date: 2017-02-14T22:29:36Z
• Authors: Fumika Matsuoka; Aya Goto; Mio Takeuchi; Hiroshi Kato; Misato Ota; Syo Hasegawa; Masayuki Miyazaki; Tomomi Tsubai; Hirotake Hida; Akihiro Mouri; Yoshinori Okamoto; Nakao Kojima; Kiyofumi Yamada; Yukihiro Noda
• Keywords: Tramadol Hydrochloride; Dose; Pain ladder

Tramadol is a weak opioid analgesic indicated for the treatment of moderate to severe cancer pain at step 2 WHO ladder. There little experience its use in Japan; there are few reported detailed surveys on usage tramadol and usefulness patients who changed from taking stronger opioids. The present study included inpatients took hydrochloride capsule Nagoya University Hospital between October 2011 March 2014; these were retrospectively examined based electronic medical records. We observed that, out 143 patients, 101 (71%) started dose 100 mg/day tramadol. Fortyeight (48%) administration opioids, which only 4 had their dosages increased 300 before being However, among whose was incidences nausea/vomiting when changing drugs significantly lower than that not taken (tramadol used group 19.4% vs non-tramadol 41.5%: P < 0.05). These results indicate incidence may be reduced opioids after having