Synthesis, Surface-Active Properties, and Antimicrobial Activities of New Double-Chain Gemini Surfactants

• DOI: 10.5650/jos.57.301
• Publication Date: 2011-06-03T14:18:02Z
• Authors: Marcelo C. Murguía; Victoria A. Vaillard; Victoria G. Sánchez; José Di Conza; Ricardo J. Grau
• Keywords: Cationic polymerization; Benzalkonium chloride

A novel series of neutral and cationic dimeric surfactants were prepared involving ketalization reaction, Williamson etherification, regioselective oxirane ring opening with primary tertiary alkyl amines. The critical micelle concentration (CMC), effectiveness surface tension reduction (gamma(CMC)), excess (Gamma), area per molecule at the interface (A) determined values indicate that is characterized by good surface-active self-aggregation properties. For first time, we reported antimicrobial activities against representative bacteria fungi for compounds. activity was found to be dependent on target microorganism (Gram-positive > Gram-negative bacteria), as well both or ionic nature (cationic neutral) chain length (di-C(12) di-C(18) di-C(8)) di-C(12) derivative have equipotent benzalkonium chloride (BAC) used standard.