Sleep Quality, Sleep Duration, and the Risk of Coronary Heart Disease: A Prospective Cohort Study With 60,586 Adults

• DOI: 10.5664/jcsm.6894
• Publication Date: 2018-01-12T20:04:14Z
• Authors: Xiang Qian Lao; Xudong Liu; Han-Bing Deng; Ta-Chien Chan; Kin Fai Ho; Feng Wang; Roel Vermeulen; Tony Tam; Martin C.S. Wong; L.A. Tse; Ly-yun Chang; Eng-Kiong Yeoh
• Keywords: Sleep

There is limited information on the relationship between risk of cardiovascular disease and joint effects sleep quality duration, especially from large, prospective, cohort studies. This study to prospectively investigate duration development coronary heart disease.This examined 60,586 adults aged 40 years or older. A self-administered questionnaire was used collect as well a wide range potential confounders. Events were self-reported in subsequent medical examinations. Two types Sleep Score (multiplicative additive) constructed reflect participants' profiles, considering both duration. The Cox regression model estimate hazard ratio (HR) 95% confidence interval (CI).A total 2,740 participants (4.5%) reported new events at follow-up. For group < 6 h/d significantly associated with an increased (HR: 1.13, CI: 1.04-1.23). However, association long (> 8 h/d) did not reach statistical significance 1.11, 0.98-1.26). quality, dreamy 1.21, 1.10-1.32) difficult fall asleep/use sleeping pills drugs 1.40, 1.25-1.56) disease. Participants lowest quartile multiplicative 1.31, 1.16-1.47) additive score compared those highest quartile.Both short poor are for does significance. Lower (poorer profile) increases disease, suggesting importance together when developing strategies improve prevention.