Comorbidity and Mortality of Narcolepsy: A Controlled Retro- and Prospective National Study
Adult
Aged, 80 and over
Male
Denmark
Comorbidity
Middle Aged
3. Good health
Young Adult
03 medical and health sciences
0302 clinical medicine
Humans
Female
Prospective Studies
Registries
Aged
Narcolepsy
Retrospective Studies
DOI:
10.5665/sleep.2706
Publication Date:
2013-05-31T19:05:52Z
AUTHORS (4)
ABSTRACT
To identify the factual morbidity and mortality of narcolepsy in a controlled design. National Patient Registry. All national diagnosed patients (757) with health information at least 3 years prior to after diagnose narcolepsy. Randomly selected four citizens (3,013) matched for age, sex, socioeconomic status from Danish Civil Registration System Statistics. Increased diagnosis included (odds ratio, 95% confidence interval):- diseases endocrine, nutritional, metabolic systems (2.10, 1.32-3.33); nervous system (5.27, 3.65-7.60); musculoskeletal (1.59, 1.23-2.05); other abnormal symptoms laboratory findings (1.66, 1.25-2.22). After diagnosis, experienced (2.31, 1.51-3.54), (9.19, 6.80-12.41), (1.70, 1.28-2.26), eye (1.67, 1.03-2.71), respiratory (1.84, 1.21-2.81). Specific diagnoses were diabetes (2.4, 1,2-4.7, P < 0.01), obesity (13.4, 3.1-57.6, 0.001), sleep apnea (19.2, 7.7-48.3, disorders (78.5, 11.8-523.3, chronic obstructive pulmonary disease (2.8, 1.4-5.8, lower back pain (2.5, 1.4-4.2, arthrosis/arthritis 1.3-4.8, observation neurological (3.5, 1.9-6.5, (1.7, 1.2-2.5, rehabilitation (5.0, 1.5-16.5, 0.005). There was trend towards greater (P = 0.07). Patients present higher several even thereafter. The rate due slightly but not significantly higher.
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