Impact of Sleep and Circadian Disruption on Energy Balance and Diabetes: A Summary of Workshop Discussions

• DOI: 10.5665/sleep.5226
• Publication Date: 2015-11-30T20:15:59Z
• Authors: Deanna M. Arble; Joseph Bass; Cecilia Diniz Behn; Matthew P. Butler; Etienne Challet; Charles Czeisler; Christopher M. De...; Joel Elmquist; Paul Franken; Michael A. Grandner; Erin C. Hanlon; Alex C. Keene; Michael J. Joyner; Ilia Karatsoreos; Philip A. Kern; Samuel Klein; Christopher J. Mo...; Allan I. Pack; Satchidananda Panda; Louis J. Ptacek; Naresh M. Punjabi; Paolo Sassone-Corsi; Frank A. Scheer; Richa Saxena; Elizabeth R. Seaq...; Matthew S. Thimgan; Eve Van Cauter; Kenneth P. Wright
• Keywords: Translational Research; Sleep

A workshop was held at the National Institute for Diabetes and Digestive Kidney Diseases with a focus on impact of sleep circadian disruption energy balance diabetes. The identified number key principles research in this area specific opportunities. Studies would be facilitated by active collaboration between investigators sleep/circadian metabolism/diabetes. There is need to translate elegant findings from basic into improving metabolic health American public. also studying humans move beyond measurements insulin glucose conduct more in-depth phenotyping. assessments rhythms as well sleep-disordered breathing incorporated all ongoing cohort studies related diabetes risk. complement short-term laboratory-based human simulated short shift work etc. subjects general population these disorders. It conceivable that chronic adaptations occur, if so, mechanisms which they occur needs understood. Particular areas opportunity are ready translation address whether CPAP treatment patients pre-diabetes obstructive apnea (OSA) prevents or delays onset temporal restricted feeding has same obesity rates it does mice.