Consensus recommendations on multiple sclerosis management in Australia and New Zealand: part 2

• DOI: 10.5694/mja2.52577
• Publication Date: 2025-02-11T10:06:00Z
• Authors: Jessica Shipley; James Beharry; Wei Yeh; Nabil Seery; Yi Chao Foong; Darshini Ayton; Pakeeran Siriratnam; Tracie Tan; Heidi Beadnall; Joshua Barton; Francesca Bridge; Robb Wesselingh; Lisa Taylor; Louise Rath; Jodi Haartsen; Mohammad Gadi; Cassie Nesbitt; Michael Zhong; Victoria Cushing; Fiona McKay; Julia Morahan; Benjamin Peter Tr...; Izanne Roos; Mark Marriott; Ai‐Lan Nguyen; Emma Downey; Joanne Crosby; Julian Bosco; Jennifer Taylor; Lauren Giles; Nevin John; Ernest Butler; Anneke van der Walt; Helmut Butzkueven; Stefan Blum; Marion Simpson; Mark Slee; Sudarshini Ramana...; Todd Hardy; Richard A L Macdo...; Katherine Buzzard; Deborah F Mason; Jeannette Lechner...; Trevor J Kilpatrick; Tomas Kalincik; Bruce V Taylor; Simon A Broadley; Stephen Reddel; Douglas Johnson; Mastura Monif
• Keywords: Delphi Method; Disease management

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system with rapidly evolving treatment options strategies. An iterative modified Delphi process was used to develop 80 consensus recommendations for management MS in Australia New Zealand. Part 1 these guidelines includes related selection initial disease-modifying therapy (DMT) MS, assessments before commencing DMT, monitoring activity on switching discontinuing DMT. This article, 2, covers risk mitigation during managing DMT special situations (including pregnancy, postpartum, breastfeeding, active infection including COVID-19, malignancy), general lifestyle measures acute relapses, symptomatic treatments. Together 1, this statement provides practical guidance clinicians involved care adults (≥ 18 years old) A safe, effective comprehensive approach crucial improving long term outcomes quality life individuals affected by MS.