Comparative analysis of antibacterial activities of Xenorhabdus species on related and non-related bacteria in vivo

• DOI: 10.5897/jma.9000026
• Publication Date: 2010-07-30
• Authors: András Fodor; Andrea M. Fodor; Steven Forst; Joseph S. Hogan; Michael G. Klein; Katalin Lengyel; Gyula Sáringer; Erko Stackebrandt; R. A. J. Taylor; Éva Lehoczky
• Keywords: Xenorhabdus; Symbiotic bacteria

Insect-nematode-bacterium mutualistic associations provide attractive systems for discovery of inter kingdom signal compounds and antibiotics. A better understanding the biological meaning inter-specific diversity with antimicrobial activity theSteinernema-symbiont Xenorhabdus bacteria may options simultaneous applications in pathogen control. Anti-bacterial activities representative strains ofXenorhabdus budapestensis, Xenorhabdus szentirmaii, innexi, ehlersii, Xenorhabdus nematophila, bovienii and Xenorhabdus cabanillassiiwere tested on non-related (Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus) bacteria each other by previously published bioassays. All active were adsorbed AmberliteR XAD1180. Chemical thermal stability antibacterial factors determined. Antibiotic produced different Xenorhabdus species against differ from those used competing bacterial genera. Anti-Xenorhabdusactivity cell-free medium sensitivity cells other Xenorhabdus strains negatively correlated in X. innexi and X. bovienii. Some remained unchanged during high pressure 121°C 10 min. The first comparative analysis intraspecific of Xenorhabdus species demonstrated that some Xenorhabdusspecies strong could be co-cultured they might simultaneously control.

Key words: Xenorhabdus, autoclaveable antimicrobials, intra-generic, cross-tolerance