Evaluation of Mechanical and Thermophysical Properties of Chitosan/Poly(DL-Lactide-co-Glycolide)/Multiwalled Carbon Nanotubes for Tissue Engineering

• DOI: 10.5923/j.materials.20150501.02
• Publication Date: 2015-01-01
• Authors: Imelda Olivas-Arm...; Elí Santos-Rodríguez; Susana Correa-Esp...; Dorian-Said Domín...; Illian Márquez-Mé...; Mónica Elvira Men...; María-Concepción ...; Santos-Adriana Ma...

Chitosan (Ch), Poly(DL-lactide-co-glycolide) (DL PLG) and Multiwalled Carbon Nanotubes (MWCNT) were used to fabricate biodegradable porous scaffolds for applications in tissue engineering by thermally induced phase separation (TIPS) technique. Through the use of a Field Emission Scanning Electron Microscopy, variation morphology was studied. The cumulative results obtained from IR X-ray diffraction spectra, TGA, DSC Mechanical properties suggest that there is chemical interaction between components composite. Also, In vitro cell culture Wistar rat's osteoblasts evaluate phenotype expression cells scaffolds, characterizing viability alkaline phosphatase (ALP) activity. Moreover, it confirmed mineralization spectra EDS analysis. Our thus show Ch/DL PLG/MWCNT are suitable biological applications.