Renal Denervation Using an Irrigated Catheter in Patients with Resistant Hypertension: A Promising Strategy?

• DOI: 10.5935/abc.20140034
• Publication Date: 2014-02-26T20:13:18Z
• Authors: Luciana Armaganijan; Rodolfo Staico; Aline Moraes; Alexandre Abizaid; Dalmo Moreira; Celso Amodeo; Márcio Sousa; Flávio Borelli; Dikran Armaganijan; J. Eduardo Sousa; Amanda Sousa
• Keywords: Renal sympathetic denervation

Systemic hypertension is an important public health problem and a significant cause of cardiovascular mortality. Its high prevalence the low rates blood pressure control have resulted in search for alternative therapeutic strategies. Percutaneous renal sympathetic denervation emerged as perspective treatment patients with resistant hypertension.To evaluate feasibility safety using irrigated catheter.Ten underwent procedure. The primary endpoint was safety, assessed by periprocedural adverse events, function vascular abnormalities at 6 months. secondary endpoints were changes levels (office ambulatory monitoring) number antihypertensive drugs months.The mean age 47.3 (± 12) years, 90% women. In first case, artery dissection occurred result trauma due to long sheath; no further cases observed after technical adjustments, thus showing effect learning curve. No thrombosis/renal infarction or death reported. Elevation serum creatinine not during follow-up. At months, one case stenosis clinical consequences diagnosed. Renal reduced office 14.6/6.6 mmHg, on average (p = 0.4 both systolic diastolic pressure). Blood monitoring decreased 28/17.6 mmHg 0.02 p 0.07 pressure, respectively). A reduction 2.1 observed.Renal feasible safe systemic arterial hypertension. Larger studies are required confirm our findings.