Is There Any Relationship between TSH Levels and Prognosis in Acute Coronary Syndrome?

• DOI: 10.5935/abc.20180019
• Publication Date: 2018-01-26T20:10:11Z
• Authors: Alexandre de Mato...; Victor Arrais Araújo; Júlia Pitombo Vella; Aline Siqueira Bossa; Bruno Biselli; Tatiana de Carval...; Maria Carolina Fe...; Carlos V. Serrano...; Christian Mueller; Mucio Tavares de ...
• Keywords: Unstable angina; Stroke; Clinical endpoint

Background: Some small studies have related higher levels of thyrotropin (TSH) to potentially worse prognosis in acute coronary syndromes. However, this relationship remains uncertain. Objective: To analyze the outcomes patients with syndromes relation value TSH at admission. Methods: Observational and retrospective study 505 (446 group I [TSH ≤ 4 mIU/L] 59 II > mIU/L]) between May 2010 2014. We obtained data about comorbidities medications used hospital. The primary endpoint was in-hospital all-cause death. secondary included combined events (death, non-fatal unstable angina or myocardial infarction, cardiogenic shock, bleeding stroke). Comparisons groups were made by one-way ANOVA chi-square test. Multivariate analysis determined logistic regression. Analyses considered significant when p < 0.05. Results: Significant differences observed regarding use enoxaparin (75.2% vs. 57.63%, = 0.02) statins (84.08% 71.19%, 0.0001), previous stroke (5.83% 15.25%, 0.007), (14.80% 27.12%, OR 3.05, 0.004), shock (4.77% 6.05%, 4.77, (12.09% 3.36, 0.012). Conclusions: In mIU/L admission, observed, incidences events, bleeding.