Photo-sensitive Antibacterial Activity of o-Phenylenediamine Carbon Dots

• DOI: 10.59796/jcst.v14n2.2024.36
• Publication Date: 2024-05-02T08:38:02Z
• Authors: Koranat Dechsri; Cheewita Suwancha...; Auayporn Apirakar...; Prasopchai Patroj...; Theerasak Rojanarata; Praneet Opanasopit; Supusson Pengnam; Thapakorn Charoen...
• Keywords: Carbon Quantum Dots; Carbon fibers

Carbon dots (CDs) are among the famous nanoparticles that have been widely developed due to high biocompatibility, low toxicity, ease of preparation, excellent photoluminescent properties, and outstanding application in biomedicine. Among various biomedical activities CDs, they can be applied as antibacterial agents because their photodynamic properties. Photodynamic therapy (PDT) has considered an alternative agent its non-invasive nature minimal side effects, especially terms improving activity against multidrug resistant bacteria when compared with traditional antibiotics. In this research, we CDs from o-phenylenediamine (OP). The (OPCDs) were synthesized via a hydrothermal method at 180°C for 3 h. After that, revealed spherical shape size range 16.38 ± 2.64 nm. minimum inhibitory concentration (MIC) bactericidal (MBC) OPCDs Staphylococcus aureus (S. aureus) both light exposure without groups significantly greater than OP solution could generate reactive oxygen species (ROS) mechanism leading cell death. Therefore, created may capability utilized treating skin infections caused mainly by S. aureus. conclusion, proposed nanomaterials enhance provide