Determination of insecticides in honey samples collected from Gümüşhane-Turkiye; Box-Behnken design evaluation of experimental parameters

• DOI: 10.61112/jiens.1567692
• Publication Date: 2025-01-23T22:05:03Z
• Authors: Erol Erçağ; Berrin Saygı Yalçın; Murat Şahin; Fehime Jülide Hız...
• Keywords: Box–Behnken design

This study deals with the investigation of cyfluthrin, cypermethrin, deltamethrin, and malathion residues in local honey samples from Gümüşhane, Turkey. The determination was performed GC/MS-MS method HP-5MS column under certain conditions: 120 ℃ oven temperature, 250 injection 121.9 kPa pressure 1.2-1.8 mL/min flow rates. were picked eighteen stations Gümüşhane. Standard addition employed chromatographic determination. No pesticide detected fifteen stations, nevertheless, subjected pesticides determined collected other three stations. residue levels varied 0.18 mg/kg to 9.50 at 1.5 rate. results also evaluated Box-Behnken Design (BBD) optimization. Multivariate experimental design (flow rate station, type) for constructing quadratic models. Regression analysis showed that predictive values yielded by model are quite close each coefficient (R2) 0.985.