Biochemical and Serological Characteristics of Incidentally Detected Chronic Hepatitis B Infection

• DOI: 10.69699/ssnimcj2024v9i2a7
• Publication Date: 2024-09-20T09:59:07Z
• Authors: M. Jahangir Alam; Masuma Mahtab; Md Muhibur Rahman; Mostak U Ahmed; M. Oliur Rahman; Malay K. S. Chowd...; Madhusudan Saha

Background: Hepatitis B virus infection is still a significant public health problem worldwide. In considerable number of cases the person remains asymptomatic, despite ongoing histological activity. Objective: This retrospective study was done to see biochemical and serological activity hepatitis in incidentally detected infected patients. Methods: cross-sectional conducted at Popular Medical Centre, Sylhet, Bangladesh, from January 2016 December 2017. Available demographic laboratory data patients chronic were retrieved record analysed using SPSS version 20. Mean SD for continuous percentage categorical calculated. Results: Total 276 patients, age ranging 13 60 years (mean 29.38), male 225 (81.5%) enrolled. Of them 147 (53.3%) 26 – 40 group. this series, 157 (56.9%) 54 (19.6%) had history saloon shave family liver disease respectively. Alanine aminotransferase (ALT) varied 15 367 iu/dl 51.54). 37 (13.4%) HBeAg positive 17 (6.2%) fatty ultrasound. HBV DNA seen 115 with 32 (27.82%) load above 100,000 copies per ml. Conclusion: We observed wide range alanine levels, notable proportion tested HBeAg. Ultrasonography revealed subset estimation showed prevalence, having high viral loads. Fibro-scan demonstrated varying degrees stiffness. These findings underscore importance comprehensive assessment monitoring infection.