Burden of influenza-associated respiratory and circulatory mortality in India, 2010-2013

• DOI: 10.7189/jogh.10.010402
• Publication Date: 2020-04-24T19:21:56Z
• Authors: Venkatesh Vinayak...; A Danielle Iuliano; Katherine Roguski; Rohit Bhardwaj; Mandeep Chadha; Siddhartha Saha; Partha Haldar; Rajeev Kumar; Vishnubhatla Sree...; Shashi Kant; Joseph Bresee; Seema Jain; Anand Krishnan
• Keywords: Adult; Male; Adolescent; Respiratory Tract Diseases; Age Factors; India; Infant; Articles; Middle Aged; Cardiovascular System; 3. Good health; Young Adult; 03 medical and health sciences; 0302 clinical medicine; Cause of Death; Child, Preschool; Influenza, Human; Humans; Female; Seasons; Child; Aged

Influenza causes substantial morbidity and mortality worldwide, however, reliable burden estimates from developing countries are limited, including India. We aimed to quantify influenza-associated for India utilizing 2010-2013 nationally representative data sources influenza virus circulation deaths.Virological were obtained the surveillance network of 10 laboratories led by National Institute Virology, Pune covering eight states 2010-2013. Death Sample Registration System same time period. Generalized linear regression with negative binomial distribution was used model weekly respiratory circulatory deaths age group proportion specimens positive subtype; excess above seasonal baseline taken as an estimate counts rates. Annual death rates 2011 Census national deaths.Estimated annual highest those ≥65 years (51.1, 95% confidence interval (CI) = 9.2-93.0 deaths/100 000 population) followed <5 (9.8, CI 0-21.8/100 000). Influenza-associated also higher among (71.8, 7.9-135.8/100 000) compared aged <65 (1.9, 0-4.6/100 Across all groups, a mean 127 092 (95% 64 046-190,139) may occur in India.Estimated high children adults years. These inform strategies prevention control India, such possible vaccine introduction.