The global burden of disease attributable to preterm birth and low birth weight in 204 countries and territories from 1990 to 2019: An analysis of the Global Burden of Disease Study

• DOI: 10.7189/jogh.14.04109
• Publication Date: 2024-07-11T20:40:50Z
• Authors: Taixiang Liu; Yanping Xu; Yanfeng Gong; Jinxin Zheng; Zheng Chen
• Keywords: Premature birth; Global Health

Abstract Background Preterm birth and low weight (PBLBW), recognised globally as primary contributors to infant mortality in children under five, have not been sufficiently investigated terms of their worldwide impact. In this study we aimed thoroughly evaluate the contemporary trends disease burden attributable PBLBW. Methods We analysed data from 204 countries territories between 1990–2019, sourced 2019 Global Burden Disease Study. global incidence disability-adjusted life years (DALYs) associated with PBLBW, stratified by age, gender, year, geographic location, alongside socio-demographic index (SDI). calculated annual percentage changes dynamic over time. employed a generalised linear model scrutinised relationship SDI attributed Results 2019, age-standardised rate deaths DALYs related PBLBW showed significant declines. Over period both death DALY rates displayed substantial downward trends, similar change observed for females males. Age-specific ratios revealed decrease PBLBW-related increasing primarily during neonatal stages (zero 27 days). The leading three causes were disorders, lower respiratory infections, sudden syndrome. Furthermore, association indicated that negatively correlated 2019. From 1990 decreased linearly most regions, except sub-Saharan Africa. Conclusions persistent is particularly pronounced neonates aged less than 28 days regions SDI. study, highlighted critical need tailored interventions at mitigating detrimental effects attain specific sustainable development goals, those centred on enhancing child survival overall well-being.